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The Relationship between Maternal Age at Birth and Intertwin Birth Weight Discordance in Korea

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KMID : 0892720170210010055
¹Ú»óÈ­ ( Park Sang-Hwa ) - ¼­¿ï´ëÇб³ ÀÇÇבּ¸¿ø Àα¸ÀÇÇבּ¸¼Ò

ÀÓ´Þ¿À ( Lim Dar-Oh ) - °øÁÖ´ëÇб³ º¸°ÇÇàÁ¤Çаú

Abstract

º» ¿¬±¸ÀÚ·á´Â Åë°èûÀÇ 2007~2014³â°£ ÃÑ 3,701,806°ÇÀÇ Ãâ»ýÀÚ·á Áß¿¡¼­ ¼­·Î ½ÖÀ» ÀÌ·é ½ÖÅÂ¾Æ 51,726½ÖÀ» ´ë»óÀ¸·Î Ãâ»ê ¿¬·É¿¡ µû¸¥ Ãâ»ýüÁß ÁßÁõºÒÀÏÄ¡ ¼öÁØ(25% ÀÌ»ó) ¹ß»ý À§Çèµµ ÃßÁ¤À» À§ÇØ ´ÙÇ×·ÎÁö½ºÆ½ ȸ±ÍºÐ¼®À» ÇÏ¿´´Ù. ½ÖÅÂ¾Æ Áß ´õ ¹«°Å¿î ½ÖžÆÀÇ Æò±Õ Ãâ»ýüÁßÀº 2.536 kg, °¡º­¿î Ãâ»ý¾ÆÀÇ Æò±ÕüÁßÀº 2.254 kgÀ̾úÀ¸¸ç, Ãâ»ýüÁß Â÷ÀÌ´Â Æò±Õ 0.282 kgÀ̾ú´Ù. ½ÖžÆÀÇ Æò±Õ Ãâ»ýüÁß ºÒÀÏÄ¡À²Àº 11.0%¿´À¸¸ç, Ãâ»ê ¿¬·É 20~29¼¼±ºÀº 10.5%, 30~34¼¼±º 11.0%, 35¼¼ ÀÌ»ó±ºÀº 11.4%¿´´Ù. Ãâ»ýüÁß ºÒÀÏÄ¡ ¼öÁØ 10% ¹Ì¸¸ÀÇ ¹ß»ý·üÀº 55.1%, ºÒÀÏÄ¡ ¼öÁØ 20~29%, ºÒÀÏÄ¡ ¼öÁØ 30% ÀÌ»óÀº °¢°¢ 10.9%, 4.4%¿´°í, Ãâ»ê ¿¬·ÉÀÌ Áõ°¡ÇÔ¿¡ µû¶ó ºÒÀÏÄ¡ ¼öÁØ 20~29% ¹× 30% ÀÌ»óÀÇ ¹ß»ý·üÀÌ Áõ°¡ÇÏ¿´´Ù. Ãâ»ýüÁß ÁßÁõºÒÀÏÄ¡ ¼öÁØ ¹ß»ý·üÀº Ãâ»ê ¿¬·É 20~29¼¼±ºÀÌ 7.7%, 30~34¼¼±º 8.3 %, 35¼¼ ÀÌ»ó±ºÀÌ 8.7%·Î Ãâ»ê ¿¬·ÉÀÌ Áõ°¡ÇÔ¿¡ µû¶ó ¹ß»ý·üÀÌ Áõ°¡ÇÏ¿´´Ù(p<0.05). Ãâ»ê ¿¬·Éº° ÁßÁõºÒÀÏÄ¡ ¼öÁØ ¹ß»ý À§Çèµµ¸¦ Ãâ»ý³âµµ, ºÎÀÇ ¿¬·É, Ãâ»ý¾ÆÀÇ ¼º, ±³À°¼öÁØ, ÀӽűⰣÀÇ º¯¼ö¸¦ ÀÌ¿ëÇÏ¿© ·ÎÁö½ºÆ½ ȸ±ÍºÐ¼® °á°ú Ãâ»ê ¿¬·É 20~29¼¼±º¿¡ ºñÇØ 30~34¼¼±ºÀÇ ÁßÁõºÒÀÏÄ¡ ¼öÁØ ¹ß»ý À§Çèµµ´Â 1.094 (95% ½Å·Ú±¸°£: 1.005~1.190), 35¼¼ ÀÌ»ó±ºÀº 1.164 (1.401~ 1.301)·Î Åë°èÀûÀ¸·Î À¯ÀÇÇÏ¿´´Ù. Ãâ»ê ¿¬·É°ú ½ÖžÆÀÇ ¼º ±¸Á¶¸¦ ¼­·Î ÅëÇÕÇÑ ºÒÀÏÄ¡ ¼öÁØ¿¡¼­ µ¿ÀÏ ¼º ±¸Á¶¿¡ ºñÇØ ´Ù¸¥ ¼º ±¸Á¶¿¡¼­ ÁßÁõºÒÀÏÄ¡ ¼öÁØ ¹ß»ý À§Çèµµ°¡ ¸ðµç ¿¬·É±º¿¡¼­ ±³Â÷ºñ°¡ Áõ°¡ÇÏ¿´´Ù(p<0.01). º» ¿¬±¸°á°ú Ãâ»ê ¿¬·ÉÀÌ Áõ°¡ÇÔ¿¡ µû¶ó ½ÖÅÂ¾Æ Ãâ»ýüÁß ÁßÁõºÒÀÏÄ¡ ¼öÁØÀÇ À§Çèµµ°¡ Áõ°¡ÇÏ¿´°í, ¼­·Î ´Ù¸¥ ¼º±¸Á¶¿¡¼­ À§Çèµµ°¡ ´õ Å©°Ô ³ªÅ¸³µ´Ù.

Purpose: To compare the relationship between intertwin birth weight discordance and maternal age at birth.

Methods: There were 51,726 pairs of twins born from 2007 to 2014 according to the birth certificate data of Korea Statistics (3,701,806 births). The data were excluded due to extra marital births, home births, and teenage births. Birth weight discordance rate (%) was calculated according to the following formula: (larger birth weight - smaller birth weight)/(birth weight of the larger twin) ¡¿100. The odds ratio of intertwin birth weight discordance rate (¡Ã25%) in maternal age at birth was calculated by logistic regression adjusted by the year of birth, gestational age, maternal education, infantile gender and paternal age.

Results: The mean birth weight of the heavier twin and that of the lighter twin were 2.536 kg and 2.254 kg, respectively. The mean birth weight difference of intertwins was 0.282 kg. The mean birth weight discordance rate by maternal age was 10.5 percent for maternal ages between 20 and 29 years, 11.0 percent for between 30 and 34 years, and 11.4 percent for 35 years and older. The frequency of birth weight discordance level of ¡Ã25 percent increased as the maternal age increased. The rate of birth weight discordance (¡Ã25%) was 7.7 percent for maternal ages between 20 and 29 years, 8.3 percent for between 30 and 34 years, and 8.7 percent in for 35 years and older. Compared with women from 20 to 29 years of age, the odds ratio of ¡Ã25 percent discordance was 1.094 (95% confidence interval: 1.005~1.190) for 30 to 34 years, and 1.164 (1.401~ 1.301) for 35 years and older. The odds ratio of ¡Ã25 percent discordance for the different-sexed twins was higher than that of the same-sexed twins in overall maternal age groups of 20 to 29 years, 30 to 34 years, and 35 years and older.

Conclusion: The risk of birth weight discordance level of ¡Ã25 percent was associated with the older maternal age. More research is required to understand the risk factors of intertwin birth weight discordance for older women.
KeyWords

birth weight discordance, maternal age, twin birth
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